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Tektook, Nihad Khalawe
- Estimation levels of Immunoglobulin and Complement in Amoebiasis Patients (Amebic Dysentery)
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Authors
Affiliations
1 Medical College, Diyala University, Diyala, IQ
2 Middle Technical University, Collage of Medical and Health Technology, Medical Laboratory Technology, IQ
1 Medical College, Diyala University, Diyala, IQ
2 Middle Technical University, Collage of Medical and Health Technology, Medical Laboratory Technology, IQ
Source
Research Journal of Pharmacy and Technology, Vol 12, No 7 (2019), Pagination: 3555-3558Abstract
Background: Amebic dysentery is an infections causing by parasitic protozoan as Entamoeba histolytica which caused light to severe intestinal damage and in sometimes its spreading to the lungs, liver, brain and others organs, so it can be causing by closely related species of Entamoeba hartmanni and Entamoeba coli are commensals. Patients and methods: The samples was collected from patient reviewers to teaching Hospital/Baghdad city and ask them about information as age, sex, educational level, Residency and Income level, During (February–May) 2018, and Stool specimens and blood (5ml) from patients suffering from diarrhea then examined all specimens within thirty min. by General stool examination (Macroscopic and Microscopic examination and determined the concentration of immunoglobulin and complement (C3 & C4) by using Single Radial Immunodiffusion (SRID). Results of current study were found higher percentage of patients in the age group (1) as 45% , whilst decreased in age groups (2) to 23% , also results showed highly percentage in male (53.4) than female (46.6)%, also percentage of infection with Entamoeba histolytica was highest in Secondary as (36.6)% and followed by Non – study (illiterate people) as ( 34.4)%, so in urban ( 74.8) % more than rural (25.2)% as well as low Income level ( 53.5%) more than both good and high income level, also this study explain all concentrations of immunoglobulin and Complement were found high significant (p<0.001) in patients group than control group, Conclusion The infection with E. histolytica were highest in young old with age range from (1-15) years who live in rural areas, and high rate concentration of IgM ; IgG and IgE. Conclusions current study, infection with E. histolytica were highest in young old with age range from (1-15) years who live in rural areas, also high rate concentration of IgG, IgM and IgE in sera of amoebiasis patients than control group as well as the complement levels (C3&C4).Keywords
Immunological Profile, Amebiasis, Entamoeba Hhstolytica.References
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- Levels of Interleukins Associated with Retinopathy in Sera of Iraqi Diabetic Patients
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Authors
Affiliations
1 Assist. Professor, M.B.Ch.B.-F.I.B.Ms.OPHTH.-F.ICO, College of Medicine, Tikrit University, IQ
2 Department of Medical Laboratory Techniques, College of Health and Medical Technique, Middle Technical University, Baghdad, IQ
1 Assist. Professor, M.B.Ch.B.-F.I.B.Ms.OPHTH.-F.ICO, College of Medicine, Tikrit University, IQ
2 Department of Medical Laboratory Techniques, College of Health and Medical Technique, Middle Technical University, Baghdad, IQ
Source
Indian Journal of Public Health Research & Development, Vol 11, No 1 (2020), Pagination: 1938-1942Abstract
The current study was carried out in Baghdad-Iraq from March to November 2018 and included 110 participant (50 patients with diabetic retinopathy, 35 without diabetic retinopathy and 25 healthy control). Diabetic patients who attended who attended specialized center for Endocrinology and diabetes in Baghdad city, all diabetic retinopathy were diagnosis by specialist ophthalmologist, control group was from blood donors who haven’t any chronic disorders. Patient other ocular, patients with previous vitrectomy, other ocular surgery were excluded from the study. Blood sample were collected from each participant in the study for determination of HbA1c, Interleukin-12 and IFN- γ levels. The study demonstrated that 29 (58%) of patients with diabetes retinopathy were males compared with 21(42%) were females, 15(42.86%) of diabetes patients without retinopathy were males compared with 10(57.14%) were females, so mean age of diabetes retinopathy patients was 55.5 ± 1.1 year while 42.8 ± 2.1 year in diabetes without retinopathy (P<0.01). The study found that of 28 (56%) of patients with diabetes retinopathy were suffered from type I diabetes compared with 22(44%) were with type II diabetes, and found that 6 (24%) of diabetes patients without retinopathy were with type I diabetes compared with 19 (76%) were with type II diabetes (P<0.01). The Group 1 shower highest mean of duration of diabetes (15 ± 4.2 year) compared with Group 2 (9.1 ± 5.2 year) (P<0.01). The study also demonstrated that mean of HbA1c was significantly (p<0.00 elevated in Group 1 followed by Group 2 and the lowest mean was in the control group (Group 3). The study found that interleukin-12 level was significantly elevated (P<0.01) in patients with diabetes retinopathy (44.03 ± 15.12 pg/ml) followed by diabetics without retinopathy (40.01 ± 22.3 pg/ml) and the lowest mean was in the control group (23.05 ± 2.1 pg/ml). The highest mean of IFN-γ was in diabetic retinopathy (39.21 ± 2.3pg/ml) followed by diabetics without retinopathy (23.22 ± 2.99 pg/ml) and the lowest mean was in the control group (8.92 ± 1.8 pg/ml) (P<0.01).Keywords
Diabetic Retinopathy, IL-12, IFN-γ, Type II DM, Type I DM.- Serum α-Klotho Level in the Patients Subjected to Hemodialysis in Association with Lipid Profile
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Authors
Affiliations
1 Kirkuk Health Directorate, Kirkuk City, IQ
2 M.B.Ch.B, M.Sc, Ph.D in Clinical Biochemistry, College of Medicine, Tikrit University, IQ
3 Ph.D in Immunology, Middle Technical University, College of Medical & Health Technology, Baghdad, IQ
4 B.Sc, M.Sc in Chemistry, Department of Biochemistry, College of Medicine, Tikrit University, IQ
1 Kirkuk Health Directorate, Kirkuk City, IQ
2 M.B.Ch.B, M.Sc, Ph.D in Clinical Biochemistry, College of Medicine, Tikrit University, IQ
3 Ph.D in Immunology, Middle Technical University, College of Medical & Health Technology, Baghdad, IQ
4 B.Sc, M.Sc in Chemistry, Department of Biochemistry, College of Medicine, Tikrit University, IQ
Source
Medico-Legal Update, Vol 20, No 1 (2020), Pagination: 1366-1372Abstract
Background: Klotho, is a protein associated with life extension plays a important role in kidney disease progression, anti-aging, anti-oxidation, modulation of ion transport, and development of disturbed mineral metabolism. The aim of the study was to measure Soluble α-Klotho(SAKL) levels in chronic kidney disease(CKD) patients before and after dialysis in relation with Lipid profile. Methods: This shortprospective hospital-based study was done in the Department of Chemistry and Biochemistry, College of medicine, Tikrit University, Tikrit, Iraq. The study was carried out for 30 patients subjected to Hemodialysis recruited from Tikrit Teaching Hospital, hemodialysis unit between 1st December, 2018 and 1st April, 2019. The study also included 30 adult persons looks healthy with no prior medical or family history of CKD as a control participated in this study. The levels of SAKL and lipid profile were measured in the serum of 30 patients, before and after Hemodialysis and compared with controls. Results: The study revealed increased in the SAKL level in CKD patients before dialysis compared to healthy control group, and decreased in group of CKD after dialysis compared to control group. Furthermore, there was a significant positive correlation of SAKL level with serum Triglyceride and Very low density lipoprotein cholesterol(VLDL-C) in CKD patients before dialysis. Conclusions: There was a highly significant relation of SAKL with lipid abnormality in CKD patients under hemodialysis.Keywords
Soluble α,-Klotho, Chronic Kidney Disease, Hemodialysis, Lipid Profile.- Immunological Role of TLR-7 , IL-17A and IL-10 in a Sample of Iraqi Chronic Renal Failure Patients
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Authors
Affiliations
1 Department of Biology, College of Science, Diyala University, Diyala, IQ
2 Department of Biotechnology, College of Science, Diyala University, Diyala, IQ
3 College of Health and Medical Technics, Middle Technical University, Baghdad, IQ
1 Department of Biology, College of Science, Diyala University, Diyala, IQ
2 Department of Biotechnology, College of Science, Diyala University, Diyala, IQ
3 College of Health and Medical Technics, Middle Technical University, Baghdad, IQ